What is the best rep range for muscle growth / hypertrophy?

There’s not a big difference in hypertrophy when comparing rep ranges in the literature.

However, it seems as if going to or almost to failure stimulates more growth per set, and the more sets you have, the more growth you get (in both muscle size and strength). The number of sets should be weighed against recovery, which is likely a skill beginner and many intermediate lifters do not have. Because of this, it is best for lifters unfamiliar with how their body responds to training to stick to a tried and true program at first.